NIPER JEE 2012 Pharma


Structure of   NIPER JEE:
The duration of NIPER-JEE entrance test is 120 minutes. The paper will hold 200 questions. For more details candidates can see the information brochure. Questions will be mainly based on M.Pharm syllabus. Many other entrance tests follow the same pattern of syllabus. It can be said that the portions for NIPER- JEE has the same syllabus as that of GATE Entrance examination. But there is small change, in NIPER more importance is given to Basic Chemistry.

Syllabus of NIPER JEE
  • Amino acids proteins
  • Aromaticity
  • Carbohydrates classification
  • Chromatography
  • Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen
  • E and Z isomerism
  • Huckel’s rule reaction mechanisms-Ester hydrolysis
  • Hybridization
  • Imine-enamine
  • Introduction to Redox reactions
  • Introduction to thermal methods of analysis
  • IUPAC nomenclature
  • Keto-enol tautomerism
  • Medicinal chemistry and Bulk Drugs
  • Mutarotation
  • Osazone test
  • Pericyclic reactions
  • Reactions like Cannizarro’s reaction
  • R and S nomenclature
  • Racemic mixture
  • Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
  • Resolution methods
  • Spectroscopy
  • Tautomerism
  • Various Heterocycles, Heterocycle synthesis, reactions

2.Natural Products:
  • Phytochemistry
  • Methods of extraction, isolation and characterization of natural products
  • Biosynthetic pathways
  • Primary metabolites
  • Secondary metabolites
  • Important therapeutic classes
  • Dietary antioxidants
  • Marine natural products
  • Plant growth regulators
  • Spectroscopy

  • Fischer, sawhorse and newmon projection formulaes
  • Biological sources of important classes of natural products
  • Standardization of natural products

4.Pharmacology and toxicology
  • Pharmacokinetics
  • Pharmacodynamics
  • Pharmacological effect, desired, undesired, toxic, adverse effects
  • Bioavailability, bioequivalence, various factors of ADME
  • Drug metabolism
  • Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways
  • Pharmacological screening
  • Mechanism of drug action
  • Drug-receptor interaction
  • Various adrenergic, cholinergic and other receptors
  • Detailed study of CNS pharmacology
  • Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure.
  • Diseases
  • Chemotherapy and pathophysiology
  • Bioassay methods
  • Pharmaceutics and formulation (Pharmaceutical Technology)
  • Drug delivery systems (DDS)
  • Carriers in DDS
  • Transdermal drug delivery systems (TDDS)
  • Parenterals
  • Drug targeting
  • Complexation
  • Solubilization
  • Polymerization
  • Viscosity measurements
  • Dosage form development- stages, implications of dosage form
  • Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities
  • Dosage forms
  • Packaging
  • Compartmental modeling
  • Bioavailability, bioequivalence studies
  • Evaluation of formulation, principles and methods of release control in oral formulations

5.Pharmaceutical analysis
  • Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability
  • Various analytical techniques
  • Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
  • Spectroscopic methods
  • Particle sizing
  • Electrophoresis
  • Chromatography- detailed
  • QA and QC: GLP, TQM, ISO system
  • Preformulation, cyclodextrin inclusion compounds
  • Solubility
  • Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
  • Dosage forms, Stages of dosage form development
  • Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay

  • Pharmaceutical technology

Genetic Engineering

  • Gene expression
  • Mutation
  • Replication
  • Transcription, translation
  • Recombination, bacteriophages


  • Fermentation
  • Methods, isolation of nucleic acids, enzymes in cloning

This will include restriction endonucleases, DNA ligase, DNA gyrase, polymerases.

Gene Therapy

  • Monoclonal antibodies
  • Insulin
  • Interferons
  • Enkephalins
  • Angiotensin analogues and other peptides.

Eligibility Criteria for NIPER

For the following B.Pharm qualification is required

  • Medicinal Chemistry
  • Natural Products
  • Pharmaceutical Analysis
  • Pharmaceutics
  • Pharm. Tech.
  • Pharmacy Practice
  • Clinical Research

For Pharmacology and  Toxicology candidates with B.V.Sc. can also apply. For specializing in Biotechnology M.Sc (Biological Sciences) qualification is also required. For Pharm. Tech M.Sc. (Organic Chemistry), B.Tech..Chemical Engg can also apply. For Pharm. Tech. candidates need to have B. Pharm. (Biotechnology) and also M.Sc.(Life Sciences).

Candidates who wish to apply for Pharmacoinformatics need to have any of the below qualifications

  • B.Pharm
  • M.Sc. (Organic/Physical Pharmaceutical Chemistry)
  • M.Sc./B.Tech. (Bioinformatics)
  • M.Sc. (Biochemistry/ Biotechnology/ Molecular Biology/ Microbiology)

For the following any of the below qualifications are required

Regulatory Toxicology

  • B.Pharm.; B.V.Sc.
  • M.Sc.(Pharmacology/ Toxicology/ Life Sciences/Biochemistry/Medical Biotechnology/Zoology);
  • M.B.B.S

Traditional Medicine

  • B.Pham
  • B.A.M.S.; M.Sc. (Botany)

Pharmaceutical Management

  • B.Pharm.
  • B.Tech (Chemical Engg or equivalent)
  • M.Sc. (Chemical/Life Sciences)

The candidate should have scored 60% or above in the qualifying examination. The candidates should also have passed in GATE or NET. Those who are appearing for their final year exam and those who are waiting for their results can also apply.

How to Apply for NIPER?

The candidates should download the form from the official website of NIPER. They should read the form carefully and fill in all the important details. They should also fill in the DD number. Next step is to upload a photo of the candidate and then submit form. They are required to take a print out of the receipt. The candidates are required to send the receipt and a Demand Draft of Rs1000/-to the registrar’s office. Those belonging to other classes should sent a Demand Draft of Rs 500/-.

Important Dates

  • Notifications will be published in April, 2012
  • Last date for online registration and submitting the form is normally in June, 2012
  • Date of NIPER JEE entrance exam will be in July, 2012
  • Results will be declared within a week of the exam

List of NIPER JEE Exam centers

  • Ahmedabad
  • Bangalore
  • Chandigarh
  • Delhi
  • Hyderabad
  • Jaipur
  • Kolkata
  • Lucknow
  • Mumbai
  • Nagpur
  • Pune
  • Trivandrum

Contact Address for NIPER JEE

  • Address: Registrar, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar - 160062, Punjab, India
  • Phone: +91(172)-2292000, 2214682-87 Extn.-2005
  • Email: registrar@niper.ac.in
  • Website: http://www.niper.ac.in

Reference Books for NIPER JEE

  • Alfred Martin
  • Remington’s Pharmaceutical Sciences
  • Notes of Gudsurkar
  • Banker series
  • Trease and Evans
  • Silverstein, Pavia, Kemp.
  • Jerry March
  • Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry)
  • I. L. Finar Vol-I and Vol-II
  • Eliel
  • Lachmann
  • Rang and Dale
  • F. S. K. Barar
  • 3Wilson and Griswold
  • Kasture (for Bioassay and Screening)
  • Vyas and Dixit
  • IP Appendices
  • Willard
  • Silverstein (Mass Spectroscopy)
  • William Kemp (NMR)
  • Pavia (for spectroscopy)
  • Alfred Martin, Chatwal (UV)
  • Garry Christen (Chemical Methods)

Study Plan for NIPER

Students who are writing the entrance exam can prepare well by concentrating more on Pharmacy subjects. They can practice last years question paper. It will be a good way to understand the syllabus and the structure of the paper. They can also visit internet and get study materials for the exam. The candidate should very well understand the importance of the exam. Students can follow a systematic method to learn their portions. They can divide the lessons and then try to learn. They should understand their strong and weak points and work accordingly. One should also take a small break in the middle. It will help to avoid boredom and fatigue. As the syllabus is vast there are chances to get bored and tired. Another useful method would be revision. It will help the students to memorize the portion well and they will become acquainted with the portions.

How and Where To Get the Results?

The results will be published on the official website of NIPER. They can follow the link given below. http://www.niper.ac.in/

Score Validity

The validity period of NIPER JEE score is a year.


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