0 Pharmacology Cholinergic Drugs Charts

• Cholinergic Spectrum of Action
• Cholinergic Receptors
  • Muscarinic Coupling
  • Nicotinic Muscle Receptor
  • Nicotinic Neuronal Receptor
  • Muscarinic Receptors
    • Type M₁
    • Type M₂
• Differences between muscarinic and nicotinic receptors: signal transduction mechanisms
• Differences between "direct" and "indirect" cholinoceptor agonists
• Choline esters: Comparisons and Contrasts
  • Potentiation by Acetylcholinesterases
• Pharmacological Effects of Cholinergic Agonists
  • Cardiovascular Effects
    • Vasodilation
    • Negative Chronotropic
    • Decreased SA and AV nodal conduction velocity
    • Negative inotropism (decreased contractility)
    • Effect on ionic currents
  • Gastrointestinal and Urinary Tracts
• Cellular Events following Cholinergic Receptor Activation
• Second Messenger Systems
• Nitric Oxide and Muscarinic Receptor Activation
• Some Cholinergic Agents

• Clinical Uses-Agonists
  • Gastrointestinal & Genitourinary
  • Opthalmological
  • Contraindications
    • Adverse Effects: Muscarinic Agonists

• Indirect-acting Cholinomimetic Drugs 
  • Acetylcholinesterase Inhibitors
    • Overview
      • "Reversible", short-acting
      • "Reversible", intermediate-acting
      • "Irreversible", long-acting
    • Indirect Acting Agents-Table
    • Pharmacokinetics
    • Clinical use in anesthesia
    • Parathion & Malathion
    • Inhibition Mechanisms
    • ACHE Locations
  • Organ Systems
    • Eye: Ophthalmological Uses
    • Gastrointestinal and Urinary Bladder
    • Myasthenia Gravis
    • Alzheimer's Disease
    • Conditions Resembling Myasthenia Gravis
• Cholinergic Antagonists
  • Antimuscarinics
  • Clinical Applications
    • CNS Overview
    • Preoperative medications
    • Management of reflex bradycardia
    • Combinations with anticholinesterase agents during pharmacological antagonism of nondepolarizing neuromuscular-blocking agents
    • Bronchodilation
    • Sedation
    • Management of gastric or intestinal hypersensitivity or secretion
    • Respiratory Tract Effects
    • Ophthalmological Effects
  • Adverse Effects
• Ganglionic Blocking Agents
• Antimuscarinic drug effects  on various organ systems